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The dermis is a layer of skin between the
epidermis and subcutaneous tissues, that consists of connective tissue and cushions the body
from stress and strain. It is divided into two layers, the superficial
area adjacent to the epidermis called the papillary region and a deep thicker area known
as the reticular dermis. The dermis is tightly connected to the epidermis
through a basement membrane. Structural components of the dermis are collagen,
elastic fibers, and extrafibrillar matrix. It also contains Mechanoreceptors that provide
the sense of touch and heat, hair follicles, sweat glands, sebaceous glands, apocrine glands,
lymphatic vessels and blood vessels. Those blood vessels provide nourishment and
waste removal for both dermal and epidermal cells. Components of the dermis
The dermis is composed of three major types of cells: fibroblasts, macrophages, and adipocytes. Apart from these cells, the dermis is also
composed of matrix components such as collagen, elastin, and extrafibrillar matrix, an extracellular
gel-like substance primarily composed of glycosaminoglycans, proteoglycans, and glycoproteins. Layers
Stratum papillare The papillary region is composed of loose
areolar connective tissue. This is named for its fingerlike projections
called papillae, that extend toward the epidermis and contain either terminal networks of blood
capillaries or tactile Meissner’s corpuscles. Reticular Layer The reticular region lies under the papillary
region and is usually much thicker. It is composed of dense irregular connective
tissue, and receives its name from the dense concentration of collagenous, elastic, and
reticular fibers that weave throughout it. These protein fibers give the dermis its properties
of strength, extensibility, and elasticity. Within the reticular region are the roots
of the hair, sebaceous glands, sweat glands, receptors, nails, and blood vessels. Additional images See also
Dermal papillae Skin
Epidermis List of cutaneous conditions

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